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Which of the following is NOT a clinical presentation of Schwachman-Diamond Syndrome?

Webbed toes or fingers

Increased energy levels

Schwachman-Diamond Syndrome is a genetic disorder that primarily affects the bone marrow and pancreas and can lead to several clinical presentations. Among these, frequent bacterial infections, failure to thrive, and certain skeletal anomalies like webbed toes or fingers are commonly recognized as manifestations of the syndrome.

Increased energy levels is not typically associated with Schwachman-Diamond Syndrome. Patients often experience fatigue and general malaise due to chronic infections and the underlying effects of the syndrome on their overall health and wellness. The condition leads to neutropenia, which increases susceptibility to infections and contributes to poor growth and development, impacting energy levels. Thus, it is not accurate to associate increased energy levels with this syndrome, making it the correct answer for what is NOT a clinical presentation of Schwachman-Diamond Syndrome.

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Frequent bacterial infections

Failure to thrive

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