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Autoimmune hemolytic anemia (AIHA) is a condition characterized by the immune system mistakenly attacking and destroying red blood cells, leading to anemia. One of the autoimmune disorders commonly associated with AIHA is systemic lupus erythematosus (SLE), often simply referred to as lupus.

Lupus is known for affecting multiple systems in the body and is characterized by the production of various autoantibodies. In patients with lupus, the presence of autoantibodies, particularly those that target red blood cell components, can lead to hemolysis. This destruction of red blood cells ultimately results in the symptoms associated with anemia, such as fatigue, pallor, and other systemic manifestations.

While other autoimmune conditions listed can cause various hematological complications, they are not as directly linked to AIHA as lupus. Understanding the relationship between autoimmune disorders and their hematological manifestations is crucial for recognizing and managing these conditions effectively.