Ace the CPHON Challenge 2026 – Elevate Your Pediatric Oncology Nursing Game!

The correct answer highlights conditions that are specifically recognized as congenital aplastic anemias. Congenital aplastic anemia is characterized by the failure of bone marrow to produce sufficient blood cells, which can be inherited or caused by genetic abnormalities.

Fanconi Anemia is indeed a classic example of congenital aplastic anemia. It is a genetic disorder that leads to bone marrow failure and is associated with increased risk of cancer and other anomalies. Dyskeratosis Congenita, another condition mentioned, also involves bone marrow dysfunction, leading to aplastic anemia, among other systemic issues. Both conditions demonstrate the inherited nature of congenital aplastic anemia, underpinning the genetic pathways that lead to failure in hematopoiesis.

In contrast, the other options include conditions that do not primarily present as congenital aplastic anemia. While Wiskott-Aldrich Syndrome is a genetic disorder affecting the immune system and involves thrombocytopenia, it does not primarily manifest as aplastic anemia. Similarly, Sickle Cell Disease is a hemoglobinopathy with different pathophysiology related to abnormal hemoglobin, and thalassemias and hemophilia are conditions primarily related to issues with hemoglobin production and clotting, respectively, rather than bone marrow failure. Thus, the